產品屬性：
產品名稱 | N-methyl Mesoporphyrin IX |
規格 | 1mg、5mg |
貨號 | EY-01Y11056 |
Cas No.: 142234-85-3
別名: N/A
化學名: 8,13-diethyl-3,7,12,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid
分子式: C35H40N4O4
分子量: 580.7
溶解度: 15mg/mL in DMSO, 20mg/mL in DMF
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N-methyl Mesoporphyrin IX is a transition state analog of porphyrin and an inhibitor of ferrochelatase.[1] It inhibits ferrochelatase in mouse liver mitochondria in vitro and in vivo, leading to an accumulation of porphyrin in isolated liver mitochondria following administration of an intravenous dose of 80 nmol. N-methyl Mesoporphyrin IX has been used as a turn-on biosensor for target DNA sequences when used in complex with a G-quadruplex-forming sequence fused to a DNA sequence complementary to the target sequence.[2] It has also been used to detect amyloid-β (1-40) (Aβ40) fibrils in vitro and in live PC12 cells overexpressing Aβ.[3] N-methyl Mesoporphyrin displays excitation/emission maxima of 399/610 nm, respectively.[4]
特別提醒公司產品僅供科研使用
