產品屬性：
產品名稱 | Ac-QPKK(Ac)-AMC |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y12597 |
Cas No.: 1387005-23-3
別名: N/A
化學名: N/A
分子式: C36H52N8O9
分子量: 740.9
溶解度: DMSO: soluble,Ethanol: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3.1 It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.1.Galleano, I., Schiedel, M., Jung, M., et al.A continuous, fluorogenic sirtuin 2 deacylase assay: Substrate screening and inhibitor evaluationJ. Med. Chem.59(3)1021-1031(2017)
特別提醒公司產品僅供科研使用
