產品屬性：
產品名稱 | Nicotinamide riboside chloride |
規格 | 10mM*1mL in Water100mg、500mg |
貨號 | EY-01Y12633 |
Cas No.: 23111-00-4
別名: N/A
化學名: N/A
分子式: C11H15ClN2O5
分子量: 290.7
溶解度: H2O : 250 mg/mL (859.99 mM)
儲存條件: Store at -20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements[1]. SIRT1 SIRT3
Nicotinamide riboside chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. Western Blot Analysis[1] Cell Line: HEK293T cells
Chronic Nicotinamide riboside chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD[+] content in a tissue-specific manner[1]. Animal Model: 10-week-old C57Bl/6J mice[1]
[1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.
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