產品屬性：
產品名稱 | PNU112455A hydrochloride |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg |
貨號 | EY-01Y12957 |
Cas No.: 21886-12-4
別名: N/A
化學名: N/A
分子式: C10H12ClN5O2S
分子量: 301.75
溶解度: DMSO: 125 mg/mL (414.25 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].[1]. Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.
特別提醒公司產品僅供科研使用
