產品屬性：
產品名稱 | PI3K/HDAC-IN-1 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y13029 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C22H25FN4O4
分子量: 428.46
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively[1].
PI3Kα|42 nM (IC50)|PI3Kβ|101 nM (IC50)|PI3Kγ|67 nM (IC50)|PI3Kδ|8.1 nM (IC50)|HDAC1|1.4 nM (IC50)|HDAC2|3.0 nM (IC50)|HDAC6|6.6 nM (IC50)|HDAC8|18 nM (IC50)
[1]. Zhang K, et al. Design, Synthesis, and Biological Evaluation of 4-Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3-Kinases and Histone Deacetylases. J Med Chem. 2019 May 29.
特別提醒公司產品僅供科研使用
