產品屬性：
產品名稱 | Napyradiomycin A1 |
規格 | 1 mg |
貨號 | EY-01Y13752 |
Cas No.: 103106-24-7
別名: N/A
化學名: N/A
分子式: C25H30Cl2O5
分子量: 481.4
溶解度: Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Napyradiomycin A1 is a fungal metabolite originally isolated from C. rubra and has diverse biological activities.1,2 It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml).1 Napyradiomycin A1 is an estrogen receptor antagonist (IC50 = 4.2 μM in rat uterine homogenates).2 It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM, respectively).31.Shiomi, K., Iinuma, H., Hamada, M., et al.Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activityJ. Antibiot. (Tokyo)39(4)487-493(1986)
2.Hori, Y., Abe, Y., Shigematsu, N., et al.Napyradiomycins A and B1: Non-steroidal estrogen-receptor antagonists produced by a StreptomycesJ. Antibiot. (Tokyo)46(12)1890-1893(1993)
3.Yamamoto, K., Tashiro, E., Motohashi, K., et al.Napyradiomycin A1, an inhibitor of mitochondrial complexes I and IIJ. Antibiot. (Tokyo)65(4)211-214(2012)
特別提醒公司產品僅供科研使用
