產品屬性：
產品名稱 | Neuromedin S (rat) (trifluoroacetate salt) |
規格 | 500μg |
貨號 | EY-01Y13810 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C193H307N57O49S?XCF3COOH
分子量: 4241.9
溶解度: Water: 1 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Neuromedin S is a neuropeptide agonist of the neuromedin U (NMU) receptors that increases calcium concentrations in CHO cells overexpressing NMU1 and NMU2 (EC50s = 65 and 91 pM, respectively). Neuromedin S (1 nmol, i.c.v.) induces phase shifts in the circadian rhythm of locomotor activity in rats without altering the circadian period length. It also suppresses food and water intake in a dose-dependent manner when administered to rats during the dark period at doses ranging from 0.1 to 5 nmol. Co-administration of neuromedin S (1 nmol, i.c.v.) inhibits the ability of neuropeptide Y , ghrelin , and agouti-related protein (ARP) to stimulate food intake in rats by greater than 50%. Neuromedin S (0.2 nmol, i.c.v.) increases vasopressin levels in rat plasma within five minutes to levels five times greater than a saline control and decreases urinary volume by 25% during the dark period.
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