產品屬性：
產品名稱 | PI3Kγ inhibitor 1 |
規格 | 5mg、10mg、50mg |
貨號 | EY-01Y13769 |
Cas No.: 1172118-03-4
別名: N/A
化學名: N/A
分子式: C32H26N8O2S
分子量: 586.67
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM.
PI3Kδ|100 nM (IC50)|PI3Kγ|100 nM (IC50)|PI3Kα|10 μM (IC50)|PI3Kβ|10 μM (IC50)
In Table 3, PI3Kγ inhibitor 1 (Compound 168) inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively. PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM.[1]. Vito J. Palombella, et al. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using pi3 kinase inhibitors. WO 2014004470 A1.
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