產品屬性：
產品名稱 | Oxanosine |
規格 | 1 mg |
貨號 | EY-01Y14554 |
Cas No.: 80394-72-5
別名: N/A
化學名: N/A
分子式: C10H12N4O6
分子量: 284.2
溶解度: N/A
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Oxanosine is an analog of guanosine that has been found in S. capreolus and has diverse biological activities, including antibacterial, antiviral, and anticancer properties.1,2 It is active against a variety of bacteria, including S. flexneri, P. mirabilis, and E. coli (MICs = 6.25, 12.5, 25 μg/ml, respectively, on peptone, but not nutrient, agar). Oxanosine inhibits replication of the HIV-1 strain IIIb in infected CEM and U937, but not H9, cells (EC50s = 7, 27, and >500 μg/ml, respectively).1 It also inhibits the growth of HeLa human cervical cancer cells (IC50 = 32 μg/ml) and reduces tumor growth in a murine L1210 lymphocytic leukemia model.21.Saito, Y., Nakamura, M., Ohno, T., et al.Syntheses of oxanosine and carbocyclic oxanosine derivatives as anti-HIV agentsJ. Antibiot. (Tokyo)53(3)309-313(2000)
2.Shimada, N., Yagisawa, N., Naganawa, H., et al.Oxanosine, a novel nucleoside from actinomycetesJ. Antibiot. (Tokyo)34(9)1216-1218(1981)
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