產品屬性：
產品名稱 | N-Despropyl Ropinirole |
規格 | 5 mg、10 mg、25 mg、50 mg |
貨號 | EY-01Y14713 |
Cas No.: 106916-16-9
別名: N/A
化學名: N/A
分子式: C13H18N2O
分子量: 218.3
溶解度: DMF: 25 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 1 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N-Despropyl ropinirole is an active metabolite of the dopamine D2 receptor agonist ropinirole .1 It increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4 receptors (EC50s = 0.63, 0.063, and 1.23 μM, respectively). N-Despropyl ropinirole is also a potential impurity found in commercial preparations of ropinirole.21.Coldwell, M.C., Boyfield, I., Brown, T., et al.Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cellsBr. J. Pharmacol.127(7)1696-1702(1999)
2.Coufal, P., Stulik, K., Claessens, H.A., et al.Separation and quantification of ropinirole and some impurities using capillary liquid chromatographyJ. Chromatogr. B Biomed. Sci. Appl.732(2)437-444(1999)
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