產品屬性：
產品名稱 | NVS-CRF38 |
規格 | 2mg、5mg、10mg、50mg、100mg |
貨號 | EY-01Y15108 |
Cas No.: 1207258-55-6
別名: N/A
化學名: N/A
分子式: C19H21N5O2
分子量: 351.4
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.IC50 value: Target: CRF1 antagonist[1]. Stringer RA, et al. Preclinical metabolism and pharmacokinetics of NVS-CRF38, a potent and orally bioavailable corticotropin-releasing factor receptor 1 antagonist. Xenobiotica. 2014 Apr 3.
[2]. Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42(7):1117-24.
特別提醒公司產品僅供科研使用
