產品屬性：
產品名稱 | Oteseconazole |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y15730 |
Cas No.: 1340593-59-0
別名: N/A
化學名: N/A
分子式: C23H16F7N5O2
分子量: 527.39
溶解度: DMSO: ≥ 270 mg/mL (511.96 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51[1][2].[1]. Warrilow AG, et al. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme. Antimicrob Agents Chemother. 2014 Dec;58(12):7121-7.
[2]. Garvey EP, et al. VT-1161 dosed once daily or once weekly exhibits potent efficacy in treatment of dermatophytosis in a guinea pig model. Antimicrob Agents Chemother. 2015 Apr;59(4):1992-7.
特別提醒公司產品僅供科研使用
