產品屬性：
產品名稱 | 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y16349 |
Cas No.: 314742-00-2
別名: N/A
化學名: N/A
分子式: C16H10N2O7
分子量: 342.3
溶解度: Chloroform: 30mg/mL,DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:2): 0.30mg/mL,DMSO: 5mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).1 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one undergoes thiolysis by hydrogen sulfide (HS1-). It displays excitation/emission maxima of 323/445 nm, respectively, in DMSO and its fluorescence intensity increases in the presence of sulfur-containing molecules.2,3,1 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one is selective for sulfur-containing molecules, including cysteine, glutathione (GSH), homocysteine, and selenocysteine and is not cytotoxic up to a concentration of 150 μg/ml.1,2References1. Chen, Y., Shang, X., Li, C., et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci. Rep. 8(1), 16159 (2018).2. Zhang, B., Ge, C., Yao, J., et al. Selective selenol fluorescent probes: Design, synthesis, structural determinants, and biological applications. J. Am. Chem. Soc. 137(2), 757-769 (2015).3. Yang, X.F., Su, Z., Liu, C., et al. A thiol-selective fluorogenic probe based on the cleavage of 4-methylumbelliferyl-2',4',6'-trinitropheyl ether. Anal. Bioanal. Chem. 396(7), 2667-2674 (2010).
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