產品屬性:
產品名稱 | PF-07104091 hydrate |
規格 | 5 mg、10 mg |
貨號 | EY-01Y16989 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C19H30N6O5

分子量: 422.48
溶解度: N/A
儲存條件: 4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).PF-07104091 hydrate (Example 13) inhibits CDK1/cyclin A2, CDK4/cyclin D1, CDK6/cyclin D3 and CDK9, with Kis of 110, 238, 465 and 117 nM, respectively[1].[1]. Douglas Carl BEHENNA, et al. Cdk2 inhibitors. WO2020157652A2.
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