產品屬性：
產品名稱 | PIK-108 |
規格 | 10mM*1 mL in DMSO、5 mg、10 mg、25 mg、50 mg、100 mg |
貨號 | EY-01Y17030 |
Cas No.: 901398-68-3
別名: N/A
化學名: N/A
分子式: C22H24N2O3
分子量: 364.44
溶解度: DMSO : 50 mg/mL (137.20 mM; Need ultrasonic)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor[1].PIK-108 (0.1-10 μM; 1 hour) blocks phosphorylation of PKB/Akt[1].[1]. Zachary A Knight, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47. [2]. Jack S Chen, et al. Characterization of structurally distinct, isoform-selective phosphoinositide 3’-kinase inhibitors in combination with radiation in the treatment of glioblastoma. Mol Cancer Ther. 2008 Apr;7(4):841-50.
特別提醒公司產品僅供科研使用
