產品屬性：
產品名稱 | 3-Hydroxycoumarin |
規格 | 5 g |
貨號 | EY-01Y17184 |
Cas No.: 939-19-5
別名: N/A
化學名: N/A
分子式: C9H6O3
分子量: 162.1
溶解度: DMF: 15 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
3-Hydroxycoumarin is a coumarin that has been found in A. reinwardtii and has diverse biological activities.1,2,3 It inhibits 15-lipoxygenase-1 (15-LO-1; IC50 = 9.5 μM).1 3-hydroxycoumarin scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM) and inhibits lipid peroxidation in vitro (IC50 = 69.07 mM).2 It is protective against UVB-induced embryotoxicity in sea urchins (E. lucunter).31.Alavi, S.J., Sadeghian, H., Seyedi, S.M., et al.A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarinChem. Biol. Drug Des.91(6)1125-1132(2017)
2.Rattanapan, J., Sichaem, J., and Tip-pyang, S.Chemical constituents and antioxidant activity from the stems of Alyxia reinwardtiiRec. Nat. Prod.6(3)288-291(2012)
3.de Araujo Leite, J.C., de Castro, T.M.X., Barbosa-Filho, J.M., et al.Photoprotective effect of coumarin and 3-hydroxycoumarin in sea urchin gametes and embryonic cellsJ. Photochem. Photobiol. B Biol.14644-51(2015)
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